XCaliber Health Raises $6.5M Seed Round
XCaliber Health, a Plano, Texas-based healthcare infrastructure startup building an agentic operating system for clinical and operational workflows, has raised $6.5 million in Seed funding.
Led by ManchesterStory, with participation from Benhamou Global Ventures (BGV) and Arka Venture Labs.
ManchesterStory is a U.S.-based venture capital firm headquartered in West Des Moines, Iowa, focused on investing in early- to growth-stage technology companies. The firm frequently leads Seed and early-stage rounds and has invested in companies focused on AI, compliance, claims technology, digital insurance infrastructure, healthcare platforms, and financial services innovation.
The company will use the funding to accelerate product development and expand deployment of its platform across healthcare organizations nationwide.
Led by CEO Prakash Khot, XCaliber Health is an agentic operating system where data, agents, and knowledge converge into one intelligence layer. The platform unifies siloed data, automates fragmented workflows, and delivers real-time intelligence across the full care continuum. Headquartered in Plano, Texas, the company delivers pre-built agents for interoperability, healthcare analytics, scheduling, prescription refills, and other operational healthcare workflows.
Funding Details
Company: XCaliber Health
Raised: $6.5M
Round: Seed
Funding Date: May 2026
Lead Investor: ManchesterStory
Additional Investors: Benhamou Global Ventures (BGV), Arka Venture Labs
Company Website: https://www.xcaliberhealth.ai/
Software Category: Healthcare AI Platform / Agentic Workflow Automation Software